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Additive neuroprotective effects of minocycline with creatine in a mouse model of ALS.

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This study indicates that minocycline selectively inhibits the microglia polarization to a proinflammatory state, and provides a basis for understanding pathogeneses of many diseases accompanied by microglial activation.

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The finding is important, the researchers said, because minocycline is readily available by prescription.

Their efficacy in the clinical studies also is very similar in terms of pocket depth reduction.

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Do not take minocycline if you are allergic to tetracycline-class drugs.

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As it stands, it has been more than twenty years ago since any new antibiotic was developed.

Steroid-sparing strategies are commonly used to control chronic inflammatory ocular conditions.

Herein, we provide the rationale for conducting a randomized, controlled trial to test the antidepressant properties of minocycline.

Minocycline produced antidepressant-like effects on the learned helplessness rats with alterations in levels of monoamine in the amygdala and no changes in BDNF levels in the hippocampus at baseline.

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